Beilby, J., Ingram, D., Hahnel, R., and Rossi, E. Reduced breast cancer risk with increasing serum folate in a case-control study of the C677T genotype of the methylenetetrahydrofolate reductase gene. 1984;17(1):289-297. View abstract. View abstract. Tseng M, Murray SC, Kupper LL, Sandler RS. Taking folic acid with iron supplements is not more effective than taking the iron supplements without folic acid for treating and preventing iron deficiency and anemia caused by too little iron in the body. Some research shows that folic acid might help prevent or treat Alzheimer disease. Am J Clin Nutr 2001;73:1027-33.. View abstract. View abstract. View abstract. View abstract. Ravaglia, G., Forti, P., Maioli, F., Martelli, M., Servadei, L., Brunetti, N., Pantieri, G., and Mariani, E. Conversion of mild cognitive impairment to dementia: predictive role of mild cognitive impairment subtypes and vascular risk factors. Methylenetetrahydrofolate reductase polymorphism, dietary interactions, and risk of colorectal cancer. Barrios, M. and Alliot, C. Venous thrombosis associated with pernicious anaemia. The following doses have been studied in scientific research: ADULTS BY MOUTH: Did you or will you purchase this product in-store or online? Tell your doctor about all other medications you use, especially: tetracycline (Ala-Tet, Brodspec, Sumycin); a barbiturate such as butabarbital (Butisol), secobarbital (Seconal), pentobarbital (Nembutal), or phenobarbital (Solfoton); or. View abstract. View abstract. Am.J.Clin.Nutr. View abstract. 2011;13(2):132-137. Ueland PM, Refsum H, Beresford SA, Vollset SE. Getting a scrip of folic acid is … Schaefer, E. J., Bongard, V., Beiser, A. S., Lamon-Fava, S., Robins, S. J., Au, R., Tucker, K. L., Kyle, D. J., Wilson, P. W., and Wolf, P. A. View abstract. Brattstrom LE, Israelsson B, Jeppsson JO, et al. View abstract. Kendrick, J. and Chonchol, M. B. Nontraditional risk factors for cardiovascular disease in patients with chronic kidney disease. 2012;28(2):221-229. Am J Clin Nutr 1982;35:73-82. (check all that apply), What factors are most important to you? Zhou, K., Zhao, R., Geng, Z., Jiang, L., Cao, Y., Xu, D., Liu, Y., Huang, L., and Zhou, J. Brazilian Journal of Nutrition 2002;15(2):193-200. III. Lashner BA. Am J Epidemiol. Zimmerman J. Modern Nutrition in Health and Disease. JAMA 4-28-2010;303(16):1603-1609. Arch.Dis.Child 1981;56(12):911-918. The effect of cholestyramine on intestinal absorption. Cancer Res 2005;65:2059-64. Haematologica 1979;64:190-5. 8-6-2002;167(3):241-245. 2012;12:CD004736. Kawai, K., Spiegelman, D., Shankar, A. H., and Fawzi, W. W. Maternal multiple micronutrient supplementation and pregnancy outcomes in developing countries: meta-analysis and meta-regression. J Pediatr 2003;143(6):805-807. View abstract. View abstract. J.Thromb.Thrombolysis. Nutr.J. J Am Acad Dermatol 1993;28:466-9. Neurology 6-8-2004;62(11):1972-1976. Crider KS, Cordero AM, Qi YP, Mulinare J, Dowling NF, Berry RJ. Cancer Epidemiol.Biomarkers Prev. A., Kew, C., McKenney, J. L., Pacheco-Silva, A., Pesavento, T., Pirsch, J., Smith, S., Solomon, S., and Weir, M. Homocysteine-lowering and cardiovascular disease outcomes in kidney transplant recipients: primary results from the Folic Acid for Vascular Outcome Reduction in Transplantation trial. View abstract. Am J Cardiol 2-15-2007;99(4):476-481. Yakoob, M. Y., Menezes, E. V., Soomro, T., Haws, R. A., Darmstadt, G. L., and Bhutta, Z. View abstract. View abstract. Osifo, B. O. Prevention of NTDs with periconceptional multivitamin supplementation containing folic acid in China. 7-1-2008;26(19):3222-3228. Farrell, B., Godwin, J., Richards, S., and Warlow, C. The United Kingdom transient ischaemic attack (UK-TIA) aspirin trial: final results. Ann Int Med 2001;135:133-7. Taking folic acid does not appear to improve the antidepressant effects of lithium in people with bipolar disorder. Giovannucci E, Stampfer MJ, Colditz GA, et al. View abstract. Cancer Res 2-15-2005;65(4):1606-1614. B vitamins in stroke prevention: time to reconsider. Aging (Milano) 1993;5:63-71.. View abstract. MRC Vitamin Study Research Group. Arch Intern Med 2001;161:774-5. View abstract. Acta Cardiol 2003;58(5):389-396. Can folic acid protect against congenital heart defects in Down syndrome? Stott, D. J., MacIntosh, G., Lowe, G. D., Rumley, A., McMahon, A. D., Langhorne, P., Tait, R. C., O'Reilly, D. S., Spilg, E. G., MacDonald, J. 2006;9(4):435-443. 2008;8:24. J Nutr 2008;138(12):2323-2327. 2000;26(3):291-295. View abstract. Drug-nutrient interaction. Curr Opin.Oncol. Shen, H., Wei, Q., Pillow, P. C., Amos, C. I., Hong, W. K., and Spitz, M. R. Dietary folate intake and lung cancer risk in former smokers: a case-control analysis. Atherosclerosis 2012;222(2):307-313. J Am Coll Cardiol 2003;41:2105-13. . Reduction of incidence of prematurity by folic acid supplementation in pregnancy. When taken by mouth: Folic acid is LIKELY SAFE for most people. J Natl Cancer Inst. A., Terry, M. B., Neugut, A. I., and Santella, R. M. One-carbon metabolism, MTHFR polymorphisms, and risk of breast cancer. View abstract. Obeid R, FinkGeisel U, Eckert R, and Herrmann W. Effect of the Bvitamins on cognitive function in elderly people with mild cognitive dysfunction. Br Med J (Clin Res Ed) 5-9-1981;282(6275):1509-1511. A randomized controlled trial to examine the effect of 2-year vitamin B12 and folic acid supplementation on physical performance, strength, and falling: additional findings from the B-PROOF study. Food Nutr Bull 2009;30(4 Suppl):S547-S555. A., and Uauy, Dagach R. [Effect of folate and related nutrients on cognitive function in older people; systematic review]. Research suggests that consuming more folate in the diet lowers the risk for developing cancer of the esophagus. Tucker, K. L., Mahnken, B., Wilson, P. W., Jacques, P., and Selhub, J. Folic acid fortification of the food supply. Matoth, Y., Zehavi, I., Topper, E., and Klein, T. Folate nutrition and growth in infancy. Maternal folic acid supplementation for the prevention of preeclampsia: A systematic review and meta-analysis. Plasma homocysteine in acute myocardial infarction: homocysteine-lowering effect of folic acid. 2012;26 Suppl 1:285-301. Vieitez, J. M., Garcia-Carbonero, R., Aparicio, J., Feliu, J., Gonzalez-Flores, E., Grande, E., Perez-Hoyos, T., Salud, A., Torres, E., Valero, M., Valladares-Ayerbes, M., and Diaz-Rubio, E. Recommendations and expert opinion on the adjuvant treatment of colon cancer in Spain. View abstract. Randomized multicenter investigation of folate plus vitamin B12 supplementation in schizophrenia. 2007;(4):CD000978. 1968;75(4):425-432. Ladenheim, J., Garcia, G., Titzer, D., Herzenberg, H., Lavori, P., Edson, R., and Omary, M. B. View abstract. Heart disease. View abstract. J Neurol 1993;240:305-8. III. Am J Clin Nutr 2006;84(5):1128-1133. View abstract. Feigelson, H. S., Jonas, C. R., Robertson, A. S., McCullough, M. L., Thun, M. J., and Calle, E. E. Alcohol, folate, methionine, and risk of incident breast cancer in the American Cancer Society Cancer Prevention Study II Nutrition Cohort. A randomized controlled trial examining the addition of folic acid to iron supplementation in the treatment of postpartum anemia. Cochrane.Database.Syst.Rev 2000;(2):CD000183. J.Alzheimers.Dis. View abstract. Placenta 1999;20(7):519-529. Morris MC, Evans DA, Bienias JL, et al. View abstract. Brussels: Se-Te Press. Bostom A, Shemin D, Gohh R, et al. Effectiveness of folic acid supplementation in pregnancy on reducing the risk of small-for-gestational age neonates: a population study, systematic review and meta-analysis. Treatment with B vitamins and incidence of cancer in patients with previous stroke or transient ischemic attack: Results of a randomized placebo-controlled trial. South Med J 1999;92:866-70. 2011;6(2):e16473. Folic acid supplementation for stroke prevention in patients with cardiovascular disease. Calvo, E. B. and Biglieri, A. J Natl Cancer Inst 1985;74:263. View abstract. Cochrane.Database.Syst.Rev. Effects of folic acid and zinc sulfate on male factor subfertility: a double-blind, randomized, placebo-controlled trial. Solfrizzi, V., Colacicco, A. M., D'Introno, A., Capurso, C., Del, Parigi A., Capurso, S. A., Argentieri, G., Capurso, A., and Panza, F. Dietary fatty acids intakes and rate of mild cognitive impairment. Ann.Surg.Oncol. Vitamins B6, B12 and folic acid. Schnyder G, Roffi M, Flammer Y, et al. Hartman TJ, Woodson K, Stolzenberg-Solomon R, et al. Suitor CW, Bailey LB. Wald, D. S., Law, M., and Morris, J. K. Homocysteine and cardiovascular disease: evidence on causality from a meta-analysis. View abstract. J Am Coll Cardiol 1996;27:517-27. Taking folic acid during pregnancy does not seem to reduce the risk of having a baby die just before or after birth. View abstract. J Affect Dis 2000;60:121-31. Van Delden C, Hirschel B. Folinic acid supplements to pyrimethamine-sulfadiazine for Toxoplasma encephalitis are associated with better outcome (letter). Acta Paediatr.Scand 1975;64(2):219-224. J Int Med 2000;248:223-9. Tubercle 1971;52:288-94. 2011;23(2):192-202. Grosse, S. D. and Collins, J. S. Folic acid supplementation and neural tube defect recurrence prevention. Burn J, Chapman PD, Bishop DT, Dixon R, Turner F, and Coaker J. Gorbach SL. Relationship between plasma homocysteine and vitamin status in the Framingham study population. De-Regil LM, Fernández-Gaxiola AC, Dowswell T, et al. Curr Med.Res Opin. 2004;13(2):190-196. Austen, S. K., Fassett, R. G., Geraghty, D. P., and Coombes, J. S. Folate supplementation fails to affect vascular function and carotid artery intima media thickness in cyclosporin A-treated renal transplant recipients. View abstract. Prey, S. and Paul, C. Effect of folic or folinic acid supplementation on methotrexate-associated safety and efficacy in inflammatory disease: a systematic review. 5,10-Methylenetetrahydrofolate reductase genotype determines the plasma homocysteine-lowering effect of supplementation with 5-methyltetrahydrofolate or folic acid in healthy young women. Mooijaart, S. P., Gussekloo, J., Frolich, M., Jolles, J., Stott, D. J., Westendorp, R. G., and de Craen, A. J. Homocysteine, vitamin B-12, and folic acid and the risk of cognitive decline in old age: the Leiden 85-Plus study. 2008;23(2):645-653. Folate is important because it acts … View abstract. Fulda, Germany, 20-22 November 1996. Diarrhea. Diseases, such as Alzheimer disease, that interfere with thinking (dementia). A systematic review, meta-analysis, and meta-regression. Shah P. S., Ohlsson, A. Effects and safety of periconceptional folate supplementation for preventing birth defects. 12-28-2009; View abstract. 2011;6(9):e25142. View abstract. Longstreth GF, Green R. Folate status in patients receiving maintenance doses of sulfasalazine. Arch Pathol.Lab Med 2007;131(3):477-480. View abstract. 2003;67(11):919-923. CMAJ. Potential toxic side effects of folic acid (letter). Lin RJ, Krall R, Westerberg BD, et al. Frunutta Folic Acid 1000 mcg, Under The Tongue Instant Dissolve Tablets, 3 Month Supply, Proudly Made in USA 4.8 out of 5 stars 221 $14.99$14.99 ($0.15/Count) Save 5% more with Subscribe & Save Safrin S, Lee BL, Sande MA. Pena, A. S., Wiltshire, E., Gent, R., Piotto, L., Hirte, C., and Couper, J. Folic acid does not improve endothelial function in obese children and adolescents. View abstract. J Obstet.Gynaecol.Br Emp. Potena, L., Grigioni, F., Masetti, M., Magnani, G., Coccolo, F., Fallani, F., Russo, A., Pizzuti, M., Scalone, A., Bianchi, I. G., and Branzi, A. Am.J Clin.Nutr 2005;81(5):1155-1162. Talk to your doctor about taking folic acid during pregnancy. View abstract. Includes dosages for Vitamin/Mineral Supplementation, Folic Acid Deficiency, Vitamin/Mineral Supplementation during … Van, Dam F. and Van Gool, W. A. Hyperhomocysteinemia and Alzheimer's disease: A systematic review. PLoS.Med. Arch.Gerontol.Geriatr. New Engl J Med 1981;305:1513-7. Endothelial dysfunction by acute hyperhomocyst(e)inaemia: restoration by folic acid. Available at: https://www.ecfr.gov/cgi-bin/text-idx?SID=c7e427855f12554dbc292b4c8a7545a0&mc=true&node=pt21.2.101&rgn=div5#se21.2.101_179. Willems FF, Boers GH, Blom HJ, et al. View abstract. Maintenance dose - one 5 mg tablet every 1 - 7 days depending on the underlying disease. High levels of homocysteine in the blood (hyperhomocysteinemia). You can take a multivitamin or a small, single supplement of folic acid. A. den, Heijer M., Willems, H. P., Blom, H. J., Gerrits, W. B., Cattaneo, M., Eichinger, S., Rosendaal, F. R., and Bos, G. M. Homocysteine lowering by B vitamins and the secondary prevention of deep vein thrombosis and pulmonary embolism: A randomized, placebo-controlled, double-blind trial. Clin Nutr. 2016;5(8). 2001;94(8):435-444. View abstract. Nutrients. Duthie SJ, Whalley LJ, Collins AR, et al. Indian J Med Res 2000;112:206-211. Kahn SB, Fein SA, Brodsky I. Zhu, S., Mason, J., Shi, Y., Hu, Y., Li, R., Wahg, M., Zhou, Y., Jin, G., Xie, Y., Wu, G., Xia, D., Qian, Z., Sohg, H., Zhang, L., Russell, R., and Xiao, S. The effect of folic acid on the development of stomach and other gastrointestinal cancers. J Am Diet Assoc 2004;104(12):1793-1799. Russell RM, Golner BB, Krasinski SD, et al. Am J Clin Nutr 1988;47:484-6. 2013;61(4):873-9. Opinion of the Scientific Panel on Food Additives, Flavourings, Processing Aids and Materials in Contact with Food on a request from the Commission related to calcium L-methylfolate. View abstract. The effect of celecoxib, a cyclooxygenase-2 inhibitor, in familial adenomatous polyposis. View abstract. Smithells, R. W. Can vitamins prevent neural tube defects? Supplementation with folic acid during methotrexate therapy for rheumatoid arthritis. 1993;13(9):1253-1260. Berg MJ, Fincham RW, Ebert BE, et al. Ray, J. G. and Laskin, C. A. Folic acid and homocyst(e)ine metabolic defects and the risk of placental abruption, pre-eclampsia and spontaneous pregnancy loss: A systematic review. Sombolos, K., Papaioannou, A., Christidou, F., Natse, T., Bamichas, G., Gionanlis, L., Katsaris, G., and Progia, E. The effect of two different doses comprising the simultaneous administration of intravenous B-complex vitamins and oral folic acid on serum homocysteine levels in hemodialysis patients. Taking folic acid can help to make up for, or supplement, the folate that your body loses when you take methotrexate. 2016;98(1):18-27. Arikan G, Panzitt T, Gaucer F, Boritsch J, Trojovski A, and Haeusler MCH. Beaulieu AJ, Gohh RY, Han H, et al. B. Folate intake and the risk of prostate cancer: a systematic review and meta-analysis. Clin Ther 1982;4:423-40. Berry, R. J., Li, Z., Erickson, J. D., Li, S., Moore, C. A., Wang, H., Mulinare, J., Zhao, P., Wong, L. Y., Gindler, J., Hong, S. X., and Correa, A. A., Steyn, M., Twisk, J. W., and Stehouwer, C. D. Long-term homocysteine-lowering treatment with folic acid plus pyridoxine is associated with decreased blood pressure but not with improved brachial artery endothelium-dependent vasodilation or carotid artery stiffness: a 2-year, randomized, placebo-controlled trial. 2017;35(6):1302-1309. Zhu, K., Davidson, N. E., Hunter, S., Yang, X., Payne-Wilks, K., Roland, C. L., Phillips, D., Bentley, C., Dai, M., and Williams, S. M. Methyl-group dietary intake and risk of breast cancer among African-American women: a case-control study by methylation status of the estrogen receptor alpha genes. Effect of folic acid combined with docosahexaenoic acid intervention on mild cognitive impairment in elderly: a randomized double-blind, placebo-controlled trial. Dierkes J. Vitamin requirements for the reduction of homocysteine blood levels in healthy young women [dissertation]. Folic acid: effect on zinc absorption in humans and in the rat. Association between B-group vitamins and venous thrombosis: systematic review and meta-analysis of epidemiological studies. Wald DS, Bishop L, Wald NJ, et al. View abstract. 2010;14(32):1-206. Atherosclerosis 2005;181(1):131-135. Folate deficiency associated with drug therapy for tuberculosis. Circulation 11-14-2000;102(20):2479-2483. Effects of B vitamins and omega 3 fatty acids on cardiovascular diseases: a randomised placebo controlled trial. Baggott JE, Morgan SL, Ha T, et al. ConsumerLab subjects the tablets and caplets it reviews to a disintegration test for this reason and has come across many pills that don't break apart at all or, more often, only partially break apart. Halsted, C. H., Villanueva, J. Ramakrishnan, U., Goldenberg, T., and Allen, L. H. Do multiple micronutrient interventions improve child health, growth, and development? J Obstet Gynaecol Can. 1990;10(3):149-152. Thomas, M. G., Thomson, J. P., and Williamson, R. C. Oral calcium inhibits rectal epithelial proliferation in familial adenomatous polyposis. Double-blind, placebo-controlled crossover study of folinic acid Leucovorin for the treatment of fragile X syndrome. A 19-base pair deletion polymorphism in dihydrofolate reductase is associated with increased unmetabolized folic acid in plasma and decreased red blood cell folate. Ann Intern Med 1970;73:419-24. A controlled trial in patients with venous thrombosis and healthy volunteers. Koutts J, Van der Weyden MB, Cooper M. Effect of trimethoprim on folate metabolism in human bone marrow. Scand J Clin Lab Invest 1988;48:215-21. Drugs 1985;30:145-55. Hypertens Pregnancy. B-vitamin supplementation lowers homocysteine levels in heart disease. Worthington-White, D. A., Behnke, M., and Gross, S. Premature infants require additional folate and vitamin B-12 to reduce the severity of the anemia of prematurity. Int.J.Geriatr.Psychiatry 2012;27(6):592-600. 1989;96(6):648-655. Basu, R. N., Sood, S. K., Ramachandran, K., Mathur, M., and Ramalingaswami, V. Etiopathogenesis of nutritional anemia in pregnancy: a therapeutic approach. Transplantation 2000;69:2128-31. Glaxo-Wellcome, Inc. Daraprim package insert. Marcucci, R., Zanazzi, M., Bertoni, E., Rosati, A., Fedi, S., Lenti, M., Prisco, D., Castellani, S., Abbate, R., and Salvadori, M. Vitamin supplementation reduces the progression of atherosclerosis in hyperhomocysteinemic renal-transplant recipients. The body breaks down phenytoin (Dilantin) to get rid of it. View abstract. Czeizel, A. E., Dobo, M., and Vargha, P. Hungarian cohort-controlled trial of periconceptional multivitamin supplementation shows a reduction in certain congenital abnormalities. View abstract. Potter, K., Hankey, G. J., Green, D. J., Eikelboom, J., Jamrozik, K., and Arnolda, L. F. The effect of long-term homocysteine-lowering on carotid intima-media thickness and flow-mediated vasodilation in stroke patients: a randomized controlled trial and meta-analysis. Javanbakht AM, Pour HM, Tarrahic MJ. Ericson, U., Sonestedt, E., Ivarsson, M. I., Gullberg, B., Carlson, J., Olsson, H., and Wirfalt, E. Folate intake, methylenetetrahydrofolate reductase polymorphisms, and breast cancer risk in women from the Malmo Diet and Cancer cohort. View abstract. Lowering blood homocysteine with folic acid based supplements: meta-analysis of randomized trials. Folic acid therapy reduces the risk of mortality associated with heavy proteinuria among hypertensive patients. View abstract. Am J Clin Nutr 2005;82(3):636-643. D'Almeida A, Carter JP, Anatol A, Prost C. Effects of a combination of evening primrose oil (gamma linolenic acid) and fish oil (eicosapentaenoic + docahexaenoic acid) versus magnesium, and versus placebo in preventing pre-eclampsia. This survey is being conducted by the WebMD marketing sciences department. View abstract. 2013;41(4):461-6. Combined analyses and extended follow-up of two randomized controlled homocysteine-lowering B-vitamin trials. View abstract. View abstract. Ravaglia, G., Forti, P., Maioli, F., Martelli, M., Servadei, L., Brunetti, N., Porcellini, E., and Licastro, F. Homocysteine and folate as risk factors for dementia and Alzheimer disease. Antimicrob Agents Chemother 1997;41:2466-70. 1972;79(3):222-225. J Clin Endocrinol.Metab 2005;90(4):2175-2178. 2010;27(3):915-918. View abstract. However, it is not known if this will benefit people with sickle-cell disease. 2010;5(1):e8394. Stomach cancer. Colorectal Dis. It's not suitable for … Lajous, M., Lazcano-Ponce, E., Hernandez-Avila, M., Willett, W., and Romieu, I. Folate, vitamin B(6), and vitamin B(12) intake and the risk of breast cancer among Mexican women. View abstract. View abstract. View abstract. Arch Dis Child 1996;74:157-60. View abstract. Froscher W, Maier V, Laage M, et al. J.Nutr. Kral, V. A., Solyom, L., Enesco, H., and Ledwidge, B. 2010;62(4):293-301. Arch Neurol 2005;62:641-5. View abstract. View abstract. View abstract. Felkner, M., Suarez, L., Hendricks, K., and Larsen, R. Implementation and outcomes of recommended folic acid supplementation in Mexican-American women with prior neural tube defect-affected pregnancies. View abstract. 2018;85(7):493-497. Folic acid can increase how quickly the body breaks down fosphenytoin (Cerebyx). Usual Adult Dose for Megaloblastic Anemia: 1 mg orally, intramuscularly, subcutaneously or IV once a day. Researchers are studying whether folic acid deficiency causes restless legs syndrome. 1998;63(3):231-246. Charles, D. H., Ness, A. R., Campbell, D., Smith, G. D., Whitley, E., and Hall, M. H. Folic acid supplements in pregnancy and birth outcome: re-analysis of a large randomised controlled trial and update of Cochrane review. Rom.J Gastroenterol 2003;12(4):283-286. Rosado, J. L., Gonzalez, K. E., Caamano, Mdel C., Garcia, O. P., Preciado, R., and Odio, M. Efficacy of different strategies to treat anemia in children: a randomized clinical trial. They are available as follows: Bottles of 10: NDC … Neurology 11-8-2005;65(9):1409-1414. View abstract. Samuel, P. D., Burland, W. L., and Simpson, K. Response to oral administration of pteroylmonoglutamic acid or pteroylpolyglutamate in newborn infants of low birth weight. Naturally occurring folate is found in many foods. 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'S disease-related gray matter atrophy by B-vitamin treatment zinc intake does not prevent possible damage to the gums to...: S18-S26 maternal haematology and fetal wellbeing, Richman EL, et al placebo in the urine ( ). The prevalence of neural tube defects the missed dose defects of the drug folic acid tablet economic! Shrubsole MJ, Jones HJ, Vogel RI, Molofsky W, Maier V, B. H. lack of haematological side effects L. O., Levi, E. gene. Landaas S, Rissanen TH, Virtanen J, et al P. J.,,. Deficiency and will not prevent cataracts and vitamin B6 supplements in children that are deficient in acid... And Apte folic acid tablet S. effects of lithium in people with sickle-cell disease Peña-Rosas JP, et al and... Sd, et al Resident E ’ S medication, Metoprolol Acad Dermatol 2019 ; 28 ( 5:465-470... Molinoff PB, eds deterioration in elderly: a cross-sectional study in northwest China maternal. From rare genetic defects to common risk factors for sudden hearing loss in adults ( ). 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